Publications
The dissemination of findings published by our faculty have contributed critical knowledge to advance the fields of geroscience and geriatric medicine.
Selected Publications
- Potdar AA, Dube S, Naito T, Li K, Botwin G, Haritunians T, Li D, Casero D, Yang S, Bilsborough J, Perrigoue JG, Denson LA, Daly M, Targan SR, Fleshner P, Braun J, Kugathasan S, Stappenbeck TS, McGovern DPB. Altered intestinal ACE2 levels are associated with inflammation, severe disease, and response to anti-cytokine therapy in inflammatory bowel disease. Gastroenterology. 2021 Feb;160(3):809-822.e7. PMID: 33160965
- Martin A, Ecklu-Mensah G, Ha C, Hendrick G, Layman DK, Gilbert J, Devkota S. Gut microbiota mediate the FGF21 adaptive stress response to chronic dietary protein restriction in mice. Nature Communications. 2021 Jun 22;12(1):3838. PMID: 34158480; PMCID: PMC8219803.
- Gaddam S, Abboud Y, Oh J, Samaan JS, Nissen NN, Lu SC, Lo SK. Incidence of pancreatic cancer by age and sex in the U.S., 2000-2018. JAMA. 2021; 326(20):2075-2077. PMID: 34689206; PMCID: PMC8543346.
- Wang Q, Kim SY, Matsushita H, Wang Z, Pandyarajan V, Matsuda M, Ohashi K, Tsuchiya T, Roh YS, Kiani C, Zhao Y, Chan M, Devkota S, Lu SC, Hayashi T, Carson DA, Seki E. Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22. Proceedings Natl Acad Sci, USA. 2021;118(1):e2020868118. PMID: 33443222; PMCID: PMC7817133.
- Shiao SL, Kershaw K, Limon JL, You S, Yoon J, Ko E, Guarnerio J, Potdar A, McGovern DPB, Bose S, Dar T, Noe P, Lee J, Kubota Y, Maymi V, Davis M, Henson R, Choi R, Yang W, Tang J, Gargus M, Prince A, Zumsteg ZS, Underhill DM. Commensal bacteria and fungi differentially regulate tumor responses to radiation therapy. Cancer Cell. 2021; 39(9):1202-1213. PMID:34329585.
- Barbier-Torres L, Murray B, Yang JW, Wang J, Matsuda M, Robinson A, Binek A, Fan W, Fernández-Ramos D, Lopitz-Otsoa F, Luque-Urbano M, Millet O, Mavila N, Peng H, Ramani K, Gottlieb R, Sun Z, Liangpunsakul S, Seki E, Van Eyk J, Mato JM, Lu SC. Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease. Nature Communication. 2022;13:557.
- Ramani K, Robinson A, Berlind J, Fan W, Abeynayake A, Binek A, Barbier-Torres L, Noureddin M, Nissen NN, Yidirim Z, Erbay E, Mato JM, Van Eyk J, Lu SC. S-adenosylmethionine inhibits la ribonucleoprotein domain family member 1 in murine liver and human liver cancer cells. Hepatology. 2022; 75(2):280-296. PMID: 34449924; PMCID: PMC8766892.
- Ha CWY, Martin A, Sepich-Poore GD, Shi B, Wang Y, Gouin K, Humphrey G, Sanders K, Ratnayake Y, Chan KSL, Hendrick G, Caldera JR, Arias C, Moskowitz JE, Ho Sui SJ, Yang S, Underhill D, Brady MJ, Knott S, Kaihara K, Steinbaugh MJ, Li H, McGovern DPB, Knight R, Fleshner P, Devkota S. Translocation of viable gut microbiota to mesenteric adipose drives formation of creeping fat in humans. Cell. 2020 Oct 29;183(3):666-683.e17. doi: 10.1016/j.cell.2020.09.009. Epub 2020 Sep 28. PMID: 32991841.
- Limon JJ, Tang J, Li D, Wolf AJ, Michelsen KS, Funari V, Gargus M, Nguyen C, Sharma P, Maymi VI, Iliev ID, Skalski JH, Brown J, Landers C, Borneman J, Braun J, Targan SR, McGovern DPB, Underhill DM. Malassezia is associated with Crohn's disease and exacerbates colitis in mouse models. Cell Host Microbe. 2019; 35(3):377-388. PMID: 30850233; PMCID: PMC6417942.
- Yang YM, Noureddin M, Liu C, Ohashi K, Kim SY, Ramnath D, Powell EE, Sweet MJ, Roh YS, Hsin IF, Deng N, Liu Z, Liang J, Mena E, Shouhed D, Schwabe RF, Jiang D, Lu SC, Noble PW, Seki E. Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis. Sci Transl Med. 2019 Jun 12;11(496):eaat9284. doi: 10.1126/scitranslmed.aat9284. PMID: 31189722.
Have Questions or Need Help?
If you have questions or would like to learn more about the CSDDRC, please contact Shelly Lu, MD, or Stephen Pandol, MD.
Davis Building, Room 2097
8700 Beverly Blvd.
Los Angeles, CA 90048