The Biobank and Research Pathology Resource collects, stores, manages and distributes biospecimens collected under Institutional Review Board (IRB)-approved protocols.
The Core currently houses more than 60,000 specimens. Specimen types in routine collections include:
- Fresh for cell isolation
- Cryopreserved for cell culture and xenografts
- Formalin-fixed and paraffin-embedded (FFPE)
- Tissue microarray
- Buffy coat
- Peripheral blood mononuclear cells (PBMCs)
- Body Fluids
- Cerebrospinal fluid
Custom Biospecimen Collection or Processing Requests
The Biobank and Research Pathology Resource can implement your IRB-approved biospecimen collection and/or processing protocol based on your specifications
- Custom biospecimen collection
- Tissue collected from the tumor site, proximal and distal to the tumor
- Custom biospecimen processing
- Peripheral blood mononuclear cell isolation
- Bone marrow mononuclear cell isolation
- Sputum cell deposition, immobilization and fixation
Prospective Collection of Remnant Tissue and Blood/Body Fluids
Clinical Annotation with Biospecimens
Researchers can request:
- Data related to tissue collection, storage and distribution
- Pathology report information
- Clinical follow-up, disease progression
- Clinical follow-up, treatment data
Tissue from Pathology Archive
Research pathologists can search for cases in the pathology department archive to provide FFPE tissue block slide recuts and/or tissue cores, as well as pathology report data.
The Biobank and Research Pathology Resource houses 30 large LN₂ tanks (with 26 racks each, 13 boxes per rack, 81 samples per box) that are filled automatically, and 25 −80°C freezers (24 racks each, 20 boxes per rack, 81 samples per box). All units are monitored with wireless probes that generate automated notifications when status changes occur.
Rapid Autopsy Program
The Rapid Autopsy Program is a new service of the Biobank and Research Pathology Resource that is initially being implemented for the brain and spinal cord from amyotrophic lateral sclerosis patients. This service will be expanded soon to include brains from Alzheimer's disease patients, as well as for various organs and tissues from control patients with no major pathology or disease. In the future, we plan to expand this service to cancer patients.
Have Questions or Need Help?
Contact us if you have questions or would like to learn more about the Biobank and Research Pathology Resource at Cedars-Sinai.
Spielberg, Room 110
8723 W. Alden Drive
Los Angeles, CA 90048