Services
The Biobank and Research Pathology Resource offers a broad range of services including DNA purification, histology, imaging and imaging analysis, and microscopy, operating on a fee-for-service (accessible for Cedars-Sinai internal users only) basis to cover collection and processing costs.
- Biorepository
- Routine or protocol-based tissue collection
- Routine or protocol-based blood collection
- Routine urine collection
- Biospecimen Procurement and Processing (Prospective)
- Routine or protocol-based tissue collection
- Routine or protocol-based blood collection
- Routine urine collection
- Other routine body fluid collection
- Live cryopreservation tissue
- Live cryopreservation blood
- Level I—Data related to tissue collection, storage and distribution
- Level II—Pathology report information
- Level III—Clinical follow-up, disease progression
- Level IV—Clinical follow-up, treatment data
- Pathology, ancillary and tissue microarray services
- Research pathologist services
- Searching cases in the pathology archive
- Archival block/slide retrieval
- Pathology review and slide annotation
- Construction of tissue microarrays (TMAs)
- TMA slide from BTRC TMA (see inventory)
- Annotation for image analysis
- Searching cases in the pathology archive
- Single and multiplex IHC staining with FFPE slides
- Tissue processing, embedding and sectioning for paraffin or frozen blocks
- Hematoxylin and eosin and other routine histology stains
- Antibody formulary
- Research instrumentation (for self-use after approved training)
- Molecular
- NanoString nCounter Digital Analyzer
- Leica CM1950 Cryostat
- Diagenode Bioruptor (Sonicator)
- QIAGEN TissueLyser LT
- Applied Biosystems QuantStudio 6 Flex Real-Time PCR System
- NanoDrop 2000c Spectrophotometer
- Covaris E220evolution Focused-Ultrasonicator
- HybEZ Oven
- QIAGEN QIAcube
- Thermo Scientific Cytospin 4 Cytocentrifuge
- Beckman Coulter Optima MAX-XP Ultracentrifuge
- NanoString nCounter Digital Analyzer
- Imaging
- Aperio AT Turbo
- TissueGnostics TissueFAXS 200
- LaVision Light Sheet UltraMicroscope
- LeicaTCS SP5 X
- Zeiss LSM 780 Confocal
- Leica DMi8 Fluorescence Microscope
- Leica LMD7000 Laser Microdissection Cell Capture System
- Olympus BX43F Brightfield Microscope
- Aperio AT Turbo
- Histology
- Microtome
- Vibratome
- Microtome
- Image services
- Imaging of immunohistochemistry (IHC) and fluorescent stains
- Live cell imaging
- Image annotation—research pathologist
- Image analysis of multiplex IHC and fluorescent stains
- Morphometric measurements
- -80°C freezer—full freezer
- -80°C freezer—rack
- Liquid nitrogen—full tank
- Liquid nitrogen—rack
- Tissue embedding and processing (FFPE and frozen)
- Tissue sectioning
- Hematoxylin and eosin (H&E) slides
- Special stains (e.g., Trichrome, Oil Red O, Prussian Blue)
- Immunohistochemistry with 1–5 antibodies
- Immunofluorescence with 1–5 antibodies
- In-situ hybridization (RNAscope)
- Microscopy
- RNA/DNA/protein extraction
- Laser capture microdissection
- Targeted gene expression profiling (ABI qPCR, NanoString)
An example workflow of how the Biobank and Research Pathology Resource can help you.
Quick Links
We use the iLab Solutions Online Core Management System to process all service requests.
Have Questions or Need Help?
Contact us if you have questions or would like to learn more about the Biobank and Research Pathology Resource at Cedars-Sinai.
Spielberg, Room 110
8723 W. Alden Drive
Los Angeles, CA 90048