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Applied Genomics, Computation & Translational Core

The Genomics Core is focused on gathering genome, transcriptome, epigenome and metagenome information for investigators. Our mission is to make these complex technologies accessible and biologically interpretable for clinical and basic research scientists.

The Genomics Core enables investigators with little experience in sample preparation, quality control or analysis to interrogate the genome. To facilitate this, we have developed general but complete wet-lab and bioinformatics analysis pipelines to accommodate standard needs and enable most genomewide investigations. For more sophisticated or custom designs, we work actively in collaboration with other Cedars-Sinai cores and resources to facilitate investigations.

The Genomics Core now offers new applications, such as single-cell RNA sequencing, microbiome profiling and targeted transcriptome resequencing for FFPE samples, using a brand-new Illumina Novaseq, MiSeq and NextSeq. The combination of instruments enables us to uniquely identify the best solutions for each project depending on sample size, sample quality, price and turnaround time.

State-of-the-art research instrumentation is available for self-use and instrumentation training for personnel who want to reserve and use instruments on their own.

View guidelines for new users to gain access to services and resources for the Applied Genomics, Computation & Translational Research Core.

The Applied Genomics, Computation & Translational Research Core offers a broad range of services including next-generation sequencing applications, quality control, high-throughput qPCR applications and bioinformatics.

Our Team

Our specialized team of physicians, scientists and technicians are uniquely qualified to manage the most complex biospecimen and instrumentation services requests.

Have Questions or Need Help?

Contact us if you have questions or would like to learn more about the Applied Genomics, Computation & Translational Core at Cedars-Sinai.

8723 Alden Drive
Steven Spielberg Building, Room 303
Los Angeles, CA 90048