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Lung Research Labs

Our labs conduct basic and translational research to develop innovative strategies for diagnosing and treating diverse lung pathologies, from asthma, influenza and pneumonia to idiopathic pulmonary fibrosis, lung cancer, lung transplantation, microbiology and pulmonary hypertension.

Primary Labs

Investigates basic mechanisms of lung injury and repair with a focus on lung epithelial cells and inflammation.

Studies the cellular and molecular signaling mechanisms that regulate host immunity to fungal infections in the lung.

Focuses on explaining the innate and adaptive immune mechanisms that drive chronic lung diseases.

Researches the role of innate immune components (Toll-like receptors) in lung injury, repair and fibrosis.

Studies how microbes evolve during chronic infections to resist therapeutic treatment and affect the immune system.

Works to clarify the molecular mechanisms of lung injury, repair and fibrosis and the role of lung stem cells pulmonary fibrosis.

Studies tissue repair, extracellular matrix, immunity and host-pathogen interactions with an emphasis on lung diseases.

Researches therapeutic targets with the potential to promote lung regeneration and improve or reverse lung disease.

Investigates how aberrant activation of the NLRP3 inflammasome may be a potential therapy for pulmonary fibrosis.

Collaborating Labs

Studies innate immunity and host-pathogen interactions as they relate to inflammatory diseases of the lungs.

Chan Laboratory

Explores cancer stem cells in the lungs and the mechanisms that drive therapeutic resistance.

Focuses on the human genome to detect susceptability genes that prompt cancer development.

Examines innate immune cells that play key roles in tissue development, repair and regeneration.

Seeks to understand how RNA/DNA-sensing mechanisms in monocytes and neutrophils drive autoimmune disease.

Develops cancer treatments through the study of heterocellular interactions in tumors that drive cancer progression.

Compares the behavior of T cells under homeostatic and chronic inflammatory conditions in mucosal sites such as the lung.

Investigates acute lung injury and the role of protein citrullination in Kawasaki disease vasculitis.

Utilizes induced pluripotent stem cells for disease modeling to study molecular mechanisms and discover new therapies.

Examines how immune systems interact with bacteria and fungi and distinguish between those that cause disease and those that make up the microbiome.

Have Questions or Need Help?

Contact us if you have questions or would like to learn more about the programs and services at the Cedars-Sinai Women’s Guild Lung Institute.

Women’s Guild Lung Institute
Pavilion, Suite 9400
127 S. San Vicente Blvd.
Los Angeles, CA 90048