Publications
See a complete PubMed list of publications by Kathrin Michelsen, PhD.
Selected Key Publications
- Tsuda M, Hamade H, Thomas LS, Salumbides BC, Potdar AA, Wong MH, Nunnelee JS, Stamps JT, Neutzsky-Wulff AV, Barrett RJ, Wang Y, Tang J, Funari VA, Targan SR, Michelsen KS. A role for BATF3 in TH9 differentiation and T-cell-driven mucosal pathologies. Mucosal Immunol. 2019 May;12(3):644-655. https://www.nature.com/articles/s41385-018-0122-4.
- Limon JJ, Tang J, Li D, Wolf AJ, Michelsen KS, Funari V, Gargus M, Nguyen C, Sharma P, Maymi VI, et al. Malassezia is associated with Crohn’s disease and exacerbates colitis in mouse models. Cell Host Microbe. 2019 Mar 13;25(3):377-388.e6. https://www.sciencedirect.com/science/article/pii/S1931312819300459.
- Doonan J, Thomas D, Wong MH, Ramage HJ, Al-Riyami L, Lumb FE, Bell KS, Fairlie-Clarke KJ, Suckling CJ, Michelsen KS, et al. Failure of the anti-inflammatory parasitic worm product ES-62 to provide protection in mouse models of Type I diabetes, multiple sclerosis and inflammatory bowel disease. Molecules. 2018 Oct 17;23(10):pii:E2669. https://www.mdpi.com/1420-3049/23/10/2669.
- Jacob N, Jacobs JP, Kumagai K, Ha CWY, Kanazawa Y, Lagishetty V, Altmayer K, Hamill AM, Von Arx A, Sartor RB, Devkota S, Braun J, Michelsen KS, et al. Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome. Mucosal Immunol. 2018 Sep;11(5):1466-1476. https://www.nature.com/articles/s41385-018-0055-y.
- Thomas LS, Targan SR, Tsuda M, Yu QT, Salumbides BC, Haritunians T, Mengesha E, McGovern DP, Michelsen KS. The TNF family member TL1A induces IL-22 secretion in committed human Th17 cells via IL-9 induction. J Leukoc Biol. 2017 Mar;101(3):727-737. http://www.jleukbio.org/content/101/3/727.
- Zonis S, Pechnick RN, Ljubimov VA, Mahgerefteh M, Wawrowsky K, Michelsen KS, Chesnokova V. Chronic intestinal inflammation alters hippocampal neurogenesis. J Neuroinflammation. 2015 Apr 3;12:65. http://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-015-0281-0.
- Michelsen KS, Wong MH, Ko B, Thomas LS, Dhall D, Targan SR. HMPL-004 (Andrographis paniculata extract) prevents development of murine colitis by inhibiting T cell proliferation and TH1/TH17 responses. Inflamm Bowel Dis. 2013; Jan;19(1):151-164. http://journals.lww.com/ibdjournal/Abstract/2013/01000/HMPL_004__Andrographis_paniculata_extract_.20.aspx.
- Lowe EL, Crother TR, Rabizadeh S, Hu B, Wang H, Chen S, Shimada K, Wong MH, Michelsen KS, Arditi M. TLR2 signaling protects mice from tumor development and growth in a mouse model of colitis-associated cancer. PLOS ONE. 2010 Sep 27;5(9):e13027. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013027.
- Michelsen KS, Thomas LS, Taylor KD, Yu QT, Mei L, Landers CJ, Derkowski C, McGovern DPB, Rotter JI, Targan SR. IBD-associated TL1A gene (TNFSF15) haplotypes determine increased expression of TL1A protein. PLOS ONE. 2009;4(3):e4719. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0004719.
- Takedatsu H, Michelsen KS, Bo W, Landers CJ, Thomas LS, Dhall D, Braun J, Targan SR. TL1A (TNFSF15) regulates the development of chronic colitis by modulating both T-helper (TH) 1 and TH17 activation. Gastroenterology. 2008 Aug;135(2):552-567. http://www.gastrojournal.org/article/S0016-5085(08)00779-8/abstract?referrer=http%3A%2F%2Fwww.doi.org%2F.
- Prehn JL, Thomas LS, Landers CJ, Yu QT, Michelsen KS, Targan SR. The T cell costimulator TL1A is induced by FcγR signaling in human monocytes and dendritic cells. J Immunol. 2007 Apr 1;178(7):4033-4038. http://www.jimmunol.org/content/178/7/4033.
- Michelsen KS, Arditi M. Toll-like receptors and innate immunity in gut homeostasis and pathology. Curr Opin Hematol. 2007 Jan;14(1):48-54. http://journals.lww.com/co-hematology/Abstract/2007/01000/Toll_like_receptors_and_innate_immunity_in_gut.10.aspx.
- Rosenkranz ME, Schulte DJ, Agle LMA, Wong MH, Zhang W, Efthimiou P, Ivashkiv L, Doherty TM, Fishbein MC, Lehman TJA, Michelsen KS, Arditi M. TLR2 and MyD88 contribute to Lactobacillus casei extract–induced focal coronary arteritis in a mouse model of Kawasaki disease. Circulation. 2005;112(19):2966. http://circ.ahajournals.org/content/112/19/2966.abstract.
- Fukata M, Eri R, Michelsen KS, Thomas LS, Hu B, Lukasek K, Nast CC, Lechago J, Xu R, Naiki Y, et al. Toll-like receptor 4 (TLR4) is required for the intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis. Am J Physiol Gastrointest Liver Physiol. 2005 May;288(5):G1055-1065. http://ajpgi.physiology.org/content/288/5/G1055.
- Michelsen KS, Doherty TM, Shah PK, Arditi M. TLR signaling: an emerging bridge from innate immunity to atherogenesis. J Immunol. 2004 Nov 15;173(10):5901-5907. http://www.jimmunol.org/content/173/10/5901.full.
Contact the Michelsen Lab
8700 Beverly Blvd.
Davis Research Building, Room 4058
Los Angeles, CA 90048