Publications
See a complete PubMed list of publications by Kenichi Shimada, PhD.
Selected Key Publications
- Martinon D, Borges VF, Gomez AC, Shimada K. Potential fast COVID-19 containment with trehalose. Front Immunol. 2020 Jul 7;11:1623.
- Nosaka N, Martinon D, Moreira D, Crother TR, Arditi M, Shimada K. Autophagy protects against developing increased lung permeability and hypoxemia by down regulating inflammasome activity and IL-1 β in LPS plus mechanical ventilation-induced acute lung injury. Front Immunol. 2020 Feb 14;11:207.
- Noval Rivas M, Wakita D, Franklin MK, Carvalho TT, Abolhesn A, Gomez AC, Fishbein MC, Chen S, Lehman TJ, Sato K, Shibuya A, Fasano A, Kiyono H, Abe M, Tatsumoto N, Yamashita M, Crother TR, Shimada K, Arditi M. Intestinal permeability and IgA provoke immune vasculitis linked to cardiovascular inflammation. Immunity. 2019 Sep 17;51(3):508-521.e6.
- Shimada K, Porritt RA, Markman JL, O'Rourke JG, Wakita D, Noval Rivas M, Ogawa C, Kozhaya L, Martins GA, Unutmaz D, et al. T-cell-intrinsic receptor interacting protein 2 regulates pathogenic T helper 17 cell differentiation. Immunity. 2018 Nov 20;49(5):873-885.e7.
- Chen S, Shimada K, Crother T, Erbay E, Shah PK, Arditi M. Chlamydia and lipids engage a common TLR4/MyD88 innate signaling pathway to promote atherogenesis. J Am Coll Cardiol. 2018 Apr 10;71(14):1553-1570.
- Domiciano TP, Wakita D, Jones HD, Crother TR, Verri WA Jr, Arditi M, Shimada K. Quercetin inhibits inflammasome activation by interfering with ASC oligomerization and prevents interleukin-1 mediated mouse vasculitis. Sci Rep. 2017 Feb 2;7:41539.
- Tumurkhuu G, Shimada K, Dagvadorj J, Crother TR, Zhang W, Luthringer D, Gottlieb RA, Chen S, Arditi M. OGG1-dependent DNA repair regulates NLRP3 inflammasome and prevents atherosclerosis. Circ Res. 2016 Sep 2;119(6):e76-e90.
- Wolf AJ, Reyes CN, Liang W, Becker C, Shimada K, Wheeler ML, Cho HC, Popescu NI, Coggeshall KM, Arditi M, Underhill DM. Hexokinase is an innate immune receptor for the detection of bacterial peptidoglycan. Cell. 2016 Jul 28;166(3):624-636.
- Jones HD, Yoo J, Crother TR, Kyme P, Ben-Shlomo A, Khalafi R, Tseng CW, Parks WC, Arditi M, Liu GY, Shimada K. Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration. PLoS One. 2015 Apr 13;10(4):e0123460.
- Jones HD, Crother TR, Gonzalez-Villalobos RA, Jupelli M, Chen S, Dagvadorj J, Arditi M, Shimada K. The NLRP3 inflammasome is required for the development of hypoxemia in LPS/mechanical ventilation acute lung injury. Am J Respir Cell Mol Biol. 2014 Feb;50(2):270-280.
- Shimada K, Crother TR, Karlin J, Dagvadorj J, Chiba N, Chen S, Ramanujan VK, Wolf AJ, Vergnes L, Ojcius DM, et al. Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity. 2012 Mar 23;36(3):401-414.
Contact the Shimada Lab
8700 Beverly Blvd.
Davis Building, Room 4008
Los Angeles, CA 90048