Gulati Lab
The Gulati Lab is a systems neuroscience laboratory studying how the brain learns, refines and recovers motor skills. We focus on the dialogue between the motor cortex and cerebellum—how these regions coordinate during skill acquisition, how sleep consolidates what was practiced during the day, and how stroke disrupts this machinery. Using electrophysiology in rodents and EEG in humans, we work from single neurons to whole networks, with the goal of developing smarter, brain-state-aware stimulation therapies for stroke rehabilitation.
Personal Statement
Our lab views stroke recovery as fundamentally a re-learning problem. The brain must rebuild the coordinated activity that once supported skilled movement—and like any learning process, this unfolds both during waking practice and during sleep. Using rodent models, we identify the circuit-level mechanisms that drive this recovery, with a particular focus on cortico-cerebellar dynamics and sleep oscillations. In parallel, our clinical EEG research in stroke patients aims to translate these findings into measurable biomarkers that can guide personalized, closed-loop stimulation therapies—delivering the right intervention to the right brain state at the right time.
Tanuj Gulati, PhD
Breakthrough Research
The Gulati Laboratory investigates how distributed brain circuits—particularly the loop between the motor cortex and cerebellum—support motor learning, sleep-dependent memory consolidation and recovery after stroke. We use electrophysiology in rodents and humans to study these processes at the level of single neurons and large-scale networks. A central finding driving our current work is that recovery after stroke mirrors the brain's natural learning process: the same oscillatory rhythms that emerge during skill acquisition and that are replayed during sleep to consolidate memories are disrupted by stroke—and restoring them at precisely the right moment can accelerate recovery.
Publications
Learn more about the recent research publications from the Gulati Lab.
Laboratory Team
Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Gulati Lab, whose dedicated efforts lead to groundbreaking discoveries.
Job Opportunities
We are actively recruiting students and postdocs to be our colleagues and expand lab knowledge and expertise to make important breakthroughs.
Collaborations
The Gulati Lab collaborates with a wide range of investigators within Cedars-Sinai and institutions around the world.
Contact the Gulati Lab
127 S. San Vicente Blvd.
Advanced Health Sciences Pavilion, Eighth Floor
Los Angeles, CA 90048