My research program is focused on providing mechanistic explanations at the cellular and circuit levels for cognitive functions such as learning and memory. Moreover, we seek to understand how basic physiological processes are corrupted in pathological states and neurological disorders. We primarily utilize electrophysiology, optogenetics and computational methods, in addition to a wide range of other techniques in human brain tissue (ex vivo) and rodents (in vivo) to interrogate mnemonic function in cortical circuits."
Breakthrough Research Areas
- Learning and memory
- Synaptic transmission and plasticity
- Cortical circuit dynamics
- Biomedical engineering
Hunt DL, Lai C, Smith RD, Lee AK, Harris TD, Barbic M.
Nat Biomed Eng. 2019 Sep;3(9):741-753. doi: 10.1038/s41551-019-0373-8. Epub 2019 Apr 1. PMID: 30936430.
Hunt DL, Linaro D, Si B, Romani S, Spruston N.
Nat Neurosci. 2018 Jul;21(7):985-995. doi: 10.1038/s41593-018-0172-7. Epub 2018 Jun 18.
Hunt DL, Puente N, Grandes P, Castillo PE.
Nat Neurosci. 2013 Aug;16(8):1049-59. doi: 10.1038/nn.3461. Epub 2013 Jul 14.