Cancer vaccines have the potential to target tumors while sparing normal tissue. We are seeking strategies to stimulate the immune system to generate anticancer responses. We are also seeking biomarkers that can help determine prognosis and treatment response. An area of particular interest is using formalin-fixed paraffin-embedded tissue to discover, validate and qualify novel biomarkers.
The Kim Laboratory is affiliated with the Samuel Oschin Comprehensive Cancer Institute and Surgery Department.
An important goal of our laboratory is to clarify the role of the immune system during cancer therapy. Standard systemic therapies have established antitumor properties; however, the immune modulating effect of traditional cytotoxic drugs and newer targeted agents has received less attention. Understanding the immune modulating properties of these agents paves the way for combination therapies that include novel cancer vaccines.
Meet Our Team
Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Kim Laboratory, whose dedicated efforts lead to groundbreaking discoveries.
Wang Y, Sparwasser T, Figlin R, Kim HL.
Cancer Res. 2014;74(8):2217-2228.
Morello M, Minciacchi VR, de Candia P, Yang J, Posadas E, Kim HL, Griffiths D, Bhowmick N, Chung L, Gandellini P, et al.
Cell Cycle. 2013;12(22):3526-3536.
Li P, Grigorenko E, Funari V, Enright E, Zhang H, Kim HL.
Contact the Kim Lab
8700 Beverly Blvd.
Davis Building, Room 5094-D
Los Angeles, CA 90048