Nicklaus Sparrow, PhD, is a research scientist and lab manager in the Lahiri Laboratory. He specializes in multiple microscopy techniques of both live and fixed samples, as well as rodent surgery and culture of primary nervous system tissues. Sparrow’s doctorate work involved studying Schwann cell biology, specifically investigating the role of actin cytoskeleton-regulating proteins, and the associated cell signaling controlling their activity, in the development of peripheral nervous system myelin. Currently, he studies both the factors that contribute to mechanical ventilation-induced delirium in neurointensive care patients as well as how to mitigate these detrimental effects with a strong focus on translating these discoveries/interventions into the clinic.
Michael Gezalian, MD, is a board-certified neurologist subspecializing in neurointensive care. After completing his neurology residency at Loma Linda University Medical Center in 2018, Gezalian pursued a clinical fellowship in neurointensive care at Cedars-Sinai to join the team of excellent clinicians at the Cedars-Sinai Neurointensive Care Unit in 2020. As a clinical fellow, he joined the Lahiri Lab and is studying the effects of antihypertensive therapies on cerebrovascular hemodynamics and cerebral perfusion. Gezalian also conducts clinical research in identifying risk factors associated with ground-level falls and subdural hematomas in the elderly, as well as investigating the potential neurological effects of early continuous renal replacement therapy initiation in post-cardiopulmonary arrest patients.
Mohammad Harun Rashid, MD, PhD, obtained his professional degree in medicine from Dhaka Medical College at the University of Dhaka, Bangladesh in 2011. He completed his PhD with distinction in biochemistry and cancer biology from Augusta University/Medical College of Georgia in 2019. There he investigated the critical role of exosomes in tumor progression and metastasis and utilized engineered exosomes for targeted theranostic application. Additionally, Rashid investigated the role of vascular mimicry in mediating antiangiogenic therapy resistance and the role of cytochrome P450 enzyme inhibitor in attenuating tumor-associated immunosuppression. He has extensive training and experience in preclinical cancer models, tumor immunology and targeted therapeutic development. His current research aims to understand the pathophysiology and molecular pathway of urinary tract infection-induced neuroinflammation and neurodegeneration.
Gena Guidry is a research associate in the Lahiri Lab. She earned her master’s degree in neuroscience from Tulane University in New Orleans, and her bachelor’s degree in biology from the University of Louisiana at Lafayette. She has been involved in diverse research projects such as numerical discrimination and evolutionary processes, the effects of space travel on biology, endogenous opioids and diabetic neuropathy, and most recently heart failure. After living and traveling a few years in Southeast Asia, Guidry is happy to have settled at Cedars-Sinai.
Faizan Anwar, BS, earned his bachelor’s degree in neuroscience from UCLA. He was previously involved in research that investigated cortical morphometric changes in patients with schizophrenia. With his interest in neuroscience and psychiatry, he is keen to study the molecular changes in the central nervous system during various psychiatric disorders. In the Lahiri Lab, Anwar is researching molecular changes in the amygdala, hippocampus and cortex that are involved in post-traumatic stress disorder in murine models of acute respiratory distress syndrome.
As a project scientist, Chengqun Huang, MD, PhD, supports the Lahiri Lab by performing rodent surgeries, such as permanent coronary artery ligation and aortic banding, to create heart disease models. He also performs echocardiography to assess cardiac function.