As an academic endocrinologist, I have a specific interest in the relationship between the gastrointestinal tract and the endocrine system. My early projects focused on gastric myoelectrical activity and glycemic control. In collaboration with researchers in the Division of Gastroenterology, we published the first paper confirming a clinical association with polycystic ovary syndrome (PCOS) and irritable bowel syndrome (IBS)."
Breakthrough Research Areas
Ruchi Mathur, MD, studies the effects of gastrointestinal microbiota on metabolic diseases such as obesity and diabetes. Defining the role of specific gut flora in the development of obesity and insulin resistance is a focus of Mathur’s research, as well as understanding the effects of the intestinal microbiome on metabolism and other medical conditions. In addition to the small intestinal microbiome, the Mathur Lab also studies polycystic ovary syndrome and the clinical phenotyping of this disorder.
Leite G, Pimentel M, Barlow GM, Chang C, Hosseini A, Wang J, Parodi G, Sedighi R, Rezaie A, Mathur R.
Cell Rep. 2021 Sep 28;36(13):109765. doi: 10.1016/j.celrep.2021.109765. PMID: 34592155.
Leite G, Pimentel M, Mathur R, Barlow GM, Chan Y, Melmed GY, Rezaie A.
Photodiagnosis Photodyn Ther. 2021 Sep;35:102457. doi: 10.1016/j.pdpdt.2021.102457.
Weitsman S, Celly S, Leite G, Mathur R, Sedighi R, Barlow GM, Morales W, Sanchez M, Parodi G, Villanueva-Millan MJ, et al.
Dig Dis Sci. 2021 Feb 3. doi: 10.1007/s10620-021-06857-y. Epub ahead of print. PMID: 33534012.