My focus is on understanding mechanisms of vascular inflammation and sex differences in atherosclerosis. Other areas being investigated are the link between autoimmune diseases, such as systemic lupus erythematosus, and increased risk of cardiovascular disease to discover new and more efficacious treatments for patients with these disorders.
- Pristane Systemic Lupus Erythematosus Mouse Model
- Innate Immunity and Atherosclerosis
- Sex-Specific Effects of the NLRP3 Inflammasome on Atherogenesis in Low-Density Lipoprotein Receptor-Deficient Mice
Meet Our Team
Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Chen Laboratory, whose dedicated efforts lead to groundbreaking discoveries.
Chen S, Shimada K, Crother T, Erbay E, Shah PK, Arditi M.
J Am Coll Cardiol. 2018 Apr 10;71(14):1553-1570.
Tumurkhuu G, Shimada K, Dagvadorj J, Crother TR, Zhang W, Luthringer D, Gottlieb RA, Chen S*, Arditi M* (*co-senior author).
Circ Res. 2016 Jul 6. pii:CIRCRESAHA.116.308362.
Tumurkhuu G, Dagvadorj J, Porritt RA, Crother TR, Shimada K, Tarling EJ, Erbay E, Arditi M, Chen S.
Cell Metab. 2018 Sep 4;28(3):432-448.e4.
Chen S, Markman J, Shimada K, Crother TR, Lane M, Abeles A, Shah PK, Arditi M.
JACC Basic Transl Sci. 2020 Jun;5(6):582-598.