Goals of the Lung Stem Cell Research Laboratory are to understand mechanisms of normal tissue maintenance and defects associated with acute and chronic lung disease. We integrate basic mechanistic studies in the research laboratory with studies that use patient-derived clinical samples to define novel therapeutic targets with potential to promote lung regeneration and ameliorate or reverse lung disease. Areas of disease focus include acute lung injury resulting from viral infection and chronic lung diseases including idiopathic pulmonary fibrosis (IPF), chronic obstructive lung disease (COPD) and lung cancer.
The Stripp Laboratory is located within the Division of Pulmonary and Critical Care Medicine in the Department of Medicine and affiliated with the Women’s Guild Lung Institute, Board of Governors Regenerative Medicine Institute and the Samuel Oschin Comprehensive Cancer Institute.
Overarching interests of the Stripp Laboratory are to define epithelial stem and progenitor cells that maintain the human lung, and to define mechanisms that regulate quiescence versus activation of these reparative cells and renewal versus differentiation in the setting of normal tissue maintenance and lung disease. Studies in the Stripp Lab benefit from the participation of patients receiving clinical care for lung disease who generously provide access to clinical samples that are used to identify candidate cellular and molecular targets for initiation and progression of chronic lung disease.
- John Belperio, MD, David Geffen School of Medicine at UCLA
- Scott Randell, PhD, University of North Carolina School of Medicine
- Brigid Hogan, PhD, Duke University School of Medicine
- Darrell Kotton, MD, Center for Regenerative Medicine of Boston University
- Jeffrey Whitsett, MD, Cincinnati Children’s Hospital
- Carla Kim, PhD, Harvard Medical School
Meet Our Team
Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Stripp Laboratory, whose dedicated efforts lead to groundbreaking discoveries.
The Stripp Laboratory has an open position for postdoctoral scientist. Apply online for one of the positions below.
Mulay A, Konda B, Garcia G Jr, Yao C, Beil S, Villalba JM, Koziol C, Sen C, Purkayastha A, Kolls JK, Pociask DA, Pessina P, de Aja JS, Garcia-de-Alba C, Kim CF, Gomperts B, Arumugaswami V, Stripp BR.
Cell Rep. 2021 May 4;35(5):109055.
Andrew K. Beppu, Juanjuan Zhao, Changfu Yao, Gianni Carraro, Edo Israely, Anna Lucia Coelho, Cory M Hogaboam, William C. Parks, Jay K. Kolls, Barry R. Stripp.
Purkayastha A, Sen C, Garcia G Jr, Langerman J, Shia DW, Meneses LK, Vijayaraj P, Durra A, Koloff CR, Freund DR, Chi J, Rickabaugh TM, Mulay A, Konda B, Sim MS, Stripp BR, Plath K, Arumugaswami V, Gomperts BN.
Cell Stem Cell. 2020 Dec 3;27(6):869-875.
Contact the Stripp Lab
127 S. San Vicente Blvd.
Advanced Health Sciences Pavilion, Room A8600
Los Angeles, CA 90048