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Research Areas

Induced Pluripotent Stem Cells (iPSCs) Applied to Disease Modeling and Personalized Therapies

Mapping the Intersection of Tissue and Cell Type-Specific Signatures of Maturation and Aging to Neurodegeneration

Motor neuron differentiated from human induced pluripotent cells express ChAT (red) and SMI-32 (green).

Nuclei extracted form adult neural tissue. (left)

Projection of cellular subtypes based on single-nuclei RNA-seq. (right)

Delineate Gene Expression Networks Conserved or Diverged Across Human and Rodent Species

Network graph of gene co-expression modules associated with motor neuron maturation and aging, whihc are also affected in amyotrophic lateral sclerosis.

Engineer Strategies to Accelerate Maturation, Aging and Late-Onset Disease in All Models

Contact the Ho Lab

127 S. San Vicente Blvd.
Pavilion, A8308
Los Angeles, CA 90048