The molecular pathology service uses state-of-the-art assays for the diagnosis, prognosis and individualized predictive response to therapy in solid tumors and hematopoietic malignancies.
The cytogenomics laboratory specializes in large-scale, genetic analysis using the tools of conventional karyotype, fluorescence in situ hybridization (FISH) and chromosomal microarrays to evaluate structural and copy number alterations throughout the genome. The molecular genetic pathology laboratory specializes in DNA-sequencing-based analysis, including polymerase chain reaction (PCR), quantitative PCR, high-resolution melting curve analysis, Sanger sequencing and next-generation sequencing to assess specific genetic alterations associated with disease. The main areas of testing in these laboratories are constitutional disease (inherited disease and prenatal diagnostics), cancer and infectious disease.
Molecular and Cytogenomics
- Atlas of Genetics and Cytogenetics in Oncology and Haematology — Search by disorder, chromosome abnormality or gene.
- OMIM (Online Mendelian Inheritance in Man) — A comprehensive, authoritative compendium of human genes and genetic phenotypes that is freely available and updated daily.
- Gene Tests — A medical genetics information resource.
Association for Molecular Pathology
The Association for Molecular Pathology (AMP) provides structure and leadership to the emerging field of molecular diagnostics. AMP includes individuals from academic and community medical centers, government and industry, including pathologist and doctoral scientist laboratory directors, basic and translational scientists, and technologists and trainees. Through the efforts of its board of directors, committees, working groups and members, AMP is the primary resource for expertise, education and collaboration in one of the fastest-growing fields in healthcare. AMP members influence policy and regulation on the national and international levels, ultimately serving to advance innovation in the field and protect patient access to high-quality, appropriate testing.
American Association for Cancer Research
The mission of the American Association for Cancer Research (AACR) is to prevent and cure cancer through research, education, communication, and collaboration. Through its programs and services, the AACR fosters research in cancer and related biomedical science; accelerates the dissemination of new research findings among scientists and others dedicated to the conquest of cancer; promotes science education and training; and advances the understanding of cancer etiology, prevention, diagnosis and treatment throughout the world.