Previous Research: GLP-1 and Gut-Brain Communication Research for Obesity and Diabetes

Ionut V, Castro AV, Woolcott OO, Stephanovski D, Iyer MS, Broussard JL, Burch M, Elazary R, Kolka CM, Mkrtchyan H, et al. Hepatic portal vein denervation impairs oral glucose tolerance, but not exenatide’s effect on glycemia. Am J Physiol Endocrinol Metab. 2014 Oct 15;307(8):E644-652. http://ajpendo.physiology.org/content/early/2014/08/07/ajpendo.00244.2014.

Ionut V, Castro AV, Woolcott OO, Stephanovski D, Iyer MS, Broussard JL, Mkrtchyan H, Burch M, Elazary R, Kirkman E, Bergman RN. Essentiality of portal vein receptors in hypoglycemic counterregulation: direct proof via denervation in male canines. Endocrinology. 2014 Apr;155(4):1247-1254. http://press.endocrine.org/doi/full/10.1210/en.2013-1794.

Ionut V, Bergman RN. Mechanisms responsible for excess weight loss after bariatric surgery. J Diabetes Sci Technol. 2011 Sep;5(5):1263-1282. http://dst.sagepub.com/content/5/5/1263.abstract.

Ionut V, Burch M, Youdim A, Bergman RN. Gastrointestinal hormones and bariatric surgery-induced weight loss. Obesity (Silver Spring). 2013 Jun;21(6):1093-1103. http://onlinelibrary.wiley.com/doi/10.1002/oby.20364/full.

Ionut V, Zheng D, Stefanovski D, Bergman RN. Exenatide can reduce glucose independent of islet hormones or gastric emptying. Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E269-277. http://ajpendo.physiology.org/content/295/2/E269.

Ionut V, Liberty IF, Hucking K, Lottati M, Stefanovski D, Zheng D, Bergman RN. Exogenously imposed postprandial-like rises in systemic glucose and GLP-1 do not produce an incretin effect, suggesting an indirect mechanism of GLP-1 action. Am J Physiol Endocrinol Metab. 2006 Oct;291(4):E779-785. http://ajpendo.physiology.org/content/291/4/E779.

Ionut V, Hucking K, Liberty IF, Bergman RN. Synergistic effect of portal glucose and glucagon-like peptide-1 to lower systemic glucose and stimulate counter-regulatory hormones. Diabetologia. 2005 May;48(5):967-975. http://link.springer.com/article/10.1007%2Fs00125-005-1709-3/fulltext.html.


Back to research